Scheimpflug Corneal Densitometry Changes After Trabeculectom
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A study was conducted to know the possible changes in Scheimpflug corneal densitometry 6 months after mitomycin C–augmented trabeculectomy and to compare these measurements with healthy controls.

Corneal densitometry was measured in 42 eyes of 42 white patients with open-angle glaucoma and 22 safe age-matched controls before and 6 months after first-time uncomplicated mitomycin C–augmented trabeculectomy. In the trabeculectomy community, researchers looked for possible associations between preoperative intraocular pressure (IOP), central corneal thickness, established disease length, gender, the type and number of substances, applications and amount of benzalkonium chloride per day, and postoperative topical cortisone usage.

Results:
--There was a statistically significant reduction of mean diurnal IOP from 19.0 ± 7.7 to 11.1 ± 7.7 mm Hg and the amount of pressure-lowering substances from 3.7 ± 1.0 to 0.1 ± 0.5.

--Densitometry measurements decreased in the entire cornea from 25.5 ± 5.7 to 23.1 ± 5.8 grayscale units with emphasis in the anterior layer.

--They returned close to normal 6 months after trabeculectomy and were not statistically significantly different compared with a healthy control group (22.8 ± 3.4 grayscale unit).

--No correlations could be found with these observations and possible causing factors studied.

Finally, 6 months after trabeculectomy, corneal densitometry, an objective and sensitive indicator of corneal clarity, returned to near-normal levels. The most likely explanations for this result are a substantial decrease in IOP and the almost complete cessation of topical antiglaucomatous substances such as benzalkonium chloride.

Source: https://journals.lww.com/corneajrnl/Abstract/2021/04000/Scheimpflug_Corneal_Densitometry_Changes_After.2.aspx
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