Scientists 3D-Print Human Heart Pump
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Scientists at the University of Minnesota have 3D printed a beating heart muscle ‘pump’ consisting of pluripotent stem cells and an extracellular matrix.

Previous attempts at printing cardiomyocytes within an extracellular matrix “ink” have struggled to achieve appropriate cell densities.

This group decided to try a different approach and cultured the stem cells within the structure, achieved an appropriate cell density.

Differentiating them in situ, the cells developed into cardiomyocytes in an environment that is closer to that of the natural heart.

The newly differentiated cells began to organize and work together. In fact, after culturing the structures for about a month, the cells began to beat together, as they would normally in the heart.

The structures that the Minnesota team has been printing are approximately 1.5 cm in size and are a closed sac that can pump fluids. The researchers intend to use the technology to study heart disease and test new therapies.

Source: https://twin-cities.umn.edu/news-events/research-brief-researchers-3d-print-working-heart-pump-real-human-cells
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