Sclerosing angiomatoid nodular transformation of the spleen:
Sclerosing angiomatoid nodular transformation (SANT) is a rare nonneoplastic splenic disorder of unknown etiopathogenesis first described by Martel et al. in 2004.

A 61-year-old Caucasian male was referred to our general surgery outpatient clinic regarding unusual splenic nodular formations described in a routine abdominal ultrasound (US). The patient’s only symptom was mild sporadic abdominal pain. He had no constitutional symptoms as asthenia or weight loss, nor had he other gastrointestinal complaints.

No blood losses or weight loss were documented. Past family history included colorectal cancer (mother and brother affected). The US report showed “enlarged spleen with five solid splenic nodules with ecographic features consistent with metastatic lesions”. Both endoscopy and colonoscopy were negative for a primary gastrointestinal tumor.

In order to clarify the US findings, an abdominal CT scan was obtained, which revealed five ring-enhancing nodular lesions 27, 20, 18, 11 and 10 mm in diameter, not clear whether they represent benign or malignant secondary lesions.

Benign tumors and nonneoplastic disorders of the spleen are uncommon entities and can very easily be mistaken by other, more common, malignant secondary lesions. SANT is one of these rare nonneoplastic splenic disorders.

Source: Journal of Surgical Case Reports

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