Sedentary leisure time of at least 8 hours per day tied to s
Among adults younger than 60 years with low physical activity, those who had at least 8 hours per day of sedentary leisure time had elevated risk for stroke, according to findings published in Stroke.

The association between physical activity (PA) and lower risk of stroke is well established, but the relationship between leisure sedentary time and stroke is less well studied.

Researchers used 9 years of the Canadian Community Health Survey between 2000 and 2012 to create a cohort of healthy individuals without prior stroke, heart disease, or cancer. We linked to hospital records to determine subsequent hospitalization or emergency department visit for stroke. They quantified the association between self-reported leisure sedentary time (categorized as less than 4, 4 to 6, 6 to 8, and 8+ hours/day) and risk of stroke using Cox regression models and competing risk regression, assessing for modification by PA, age, and sex and adjusting for demographic, vascular, and social factors.

Results:
-- There were 143 180 people in our cohort and 2965 stroke events in follow-up.

-- Median time from survey response to stroke was 5.6 years. There was a 3-way interaction between leisure sedentary time, PA, and age.

-- The risk of stroke with 8+ hours of sedentary time was significantly elevated only among individuals less than 60 years of age who were in the lowest PA quartile.

-- The association was significant across multiple sensitivity analyses, including adjustment for mood disorders and when accounting for the competing risk of death.

Conclusively, excess leisure sedentary time of 8+ hours/day is associated with increased risk of long-term stroke among individuals less than 60 years of age with low PA. These findings support efforts to enhance PA and reduce sedentary time in younger individuals.

Source: https://www.ahajournals.org/doi/10.1161/STROKEAHA.121.034985
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