Self Monitoring Of Glucose Levels Associated With HBV Infect
A group of researchers from China conducted a cross-sectional comparative study to explore the association between self-monitoring of blood glucose (SMBG) and hepatitis B virus (HBV) infection among people with diabetes. For the study 408 patients with diabetes were systematically recruited, and based on their characteristics 408 people without diabetes were randomly matched 1:1. Venous blood was collected for HBV serological testing and blood glucose testing.The primary outcome was comparison of hepatitis B surface antigen (HBsAg) positive rates between the two groups. The secondary outcome was the relationship between frequency of SMBG and HBsAg positivity. Results showed that HBsAg positive rate in people without diabetes was 2.0% and in those with diabetes was 4.2%. Also, for people without diabetes or patients with diabetes, higher frequency of SMBG was associated with higher HBsAg positive rate. Increase in the duration of diabetes were correlated with increasing rates of HBsAg. Compared with people without diabetes, logistic regression identified an association between diabetes and HBV infection. It was concluded that routine blood glucose monitoring at home was associated with HBV infection, which meant people with diabetes may be at high risk of HBV infection.

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https://doi.org/10.1136/bmjopen-2020-048463
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