Self-healing CD30- T-clonal proliferation of the tongue: report of an extremely rare case
Aug 19, 2019346 viewsThe etiology of traumatic ulcerative granulomas with stromal eosinophilia (TUGSE) is not clear, traumatic irritation having advocated as the most likely cause.
A 57 year-old woman was referred to the Unit of Oral Medicine and Laser Surgery of the University of Parma, Italy, because of a 15 days standing, painful lesion on the right border of the tongue. Clinical investigation revealed the presence of a round, nodular, ulcerated, slightly exophytic lesion of the right posterior border of the tongue, in proximity of the ventral portion.
Gauze swiping did not remove the fibrin-like material from the surface of the lesion. Histological features included a polymorphic lymphocytic infiltrate with slight eosinophilia (Fig. 3). Epithelium presented ulceration with signs of pseudoepitheliomatous hyperplasia. Imaging and laboratory work-up was negative.
In contrast with the seriousness of the clinical appearance, complete remission with mucosal healing spontaneously occurred in 15 days.
Source: BMC Oral Health
Read more: https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-019-0875-5
A 57 year-old woman was referred to the Unit of Oral Medicine and Laser Surgery of the University of Parma, Italy, because of a 15 days standing, painful lesion on the right border of the tongue. Clinical investigation revealed the presence of a round, nodular, ulcerated, slightly exophytic lesion of the right posterior border of the tongue, in proximity of the ventral portion.
Gauze swiping did not remove the fibrin-like material from the surface of the lesion. Histological features included a polymorphic lymphocytic infiltrate with slight eosinophilia (Fig. 3). Epithelium presented ulceration with signs of pseudoepitheliomatous hyperplasia. Imaging and laboratory work-up was negative.
In contrast with the seriousness of the clinical appearance, complete remission with mucosal healing spontaneously occurred in 15 days.
Source: BMC Oral Health
Read more: https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-019-0875-5
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