Sexual function and sexually related personal distress up to
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Premenopausal risk-reducing bilateral salpingo-oophorectomy (RRBSO) may impair sexual function.

A prospective observational study of 73 premenopausal women at elevated risk of ovarian cancer planning RRBSO and 68 premenopausal controls at population risk of ovarian cancer was conducted. Participants completed the Female Sexual Function Index and the Female Sexual Distress Scale-Revised. Change from baseline in sexual function following RRBSO was compared with controls at 12 months according to estrogen therapy use.

- Baseline sexual function domains did not differ between controls and those who underwent RRBSO and subsequently initiated or did not initiate estrogen therapy.

- At 12 months, sexual desire and satisfaction were unchanged in the RRBSO group compared with controls.

- After RRBSO, nonestrogen therapy users demonstrated significant impairment in sexual arousal, lubrication, orgasm, and pain compared with controls.

- Although sexually related personal distress may have been more likely after RRBSO, irrespective of estrogen therapy use, there was insufficient data to formally test this effect.

Conclusively, the findings suggest premenopausal RRBSO adversely affects several aspects of sexual function which may be mitigated by the use of estrogen therapy.

Menopause
Source: https://journals.lww.com/menopausejournal/Abstract/2021/07000/A_prospective_controlled_study_of_sexual_function.5.aspx
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