Short-term and long-term outcomes after laparoscopic surgery
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There has been an increase in the percentage of elderly patients with colorectal cancer (CRC). The short- and long-term outcomes of laparoscopic surgery for elderly patients with CRC aged over 80 years is safe, finds a study.

This study included 529 patients who underwent laparoscopic resection for clinical stage 0–III CRC. Propensity score matching (PSM) was used to create balanced cohorts of the elderly and the non-elderly. Their clinical outcomes were compared after PSM.

- After matching, carcinoembryonic antigen (CEA) level was higher in the non-elderly group, and adjuvant chemotherapy was less frequently employed in the elderly group.

- D3 dissection was performed more frequently and the number of the harvested lymph nodes tended to be larger in the non-elderly group.

- There was no significant difference in the rates of postoperative complications, reoperation within 30 days, and 30-day mortality between the groups.

- The 5-year relapse-free survival rate was not statistically different between the two groups.

- The multivariate analyses for the whole cohort showed that the factors of sex, tumor location, operation time, and conversion to open surgery, but not the age, were significant predictors of postoperative complications.

Conclusively, laparoscopic surgery for colorectal cancer patients aged over 80 years is technically and oncologically safe.

International Journal of Colorectal Disease
Source: https://doi.org/10.1007/s00384-021-03973-z
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