Simultaneous diagnosis of familial achalasia
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Achalasia is a disease characterized by impaired peristalsis of the esophageal body with relaxation failure of the lower esophageal sphincter (LES), lack of the first peristaltic wave of the esophagus, synchronized contraction, and histologically by the disappearance and degeneration of the Auerbach nerve plexus in the tunica muscularis esophagi; however, the cause of neurodegeneration is unknown. Currently, the involvement of viruses, immune disorders, genes, gastrointestinal hormones, and others have been implicated; however, the details thereof are unknown. We hereby report on two cases we experienced in which a simultaneous diagnosis of familial achalasia was made...

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