Single-layer Inverted Internal Limiting Membrane Flap and Co
A Study was conducted to compare the outcomes of using an internal limiting membrane (ILM) flap and the conventional ILM peel technique for small- or medium-sized full-thickness macular hole (FTMH) repair.

Eyes with an FTMH less than 400 micro-m that underwent vitrectomy with either a single-layer inverted ILM flap or an ILM peel were enrolled. Best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) measurements were obtained preoperatively and at 1, 3, 6, and 12 months postoperatively.

--Primary hole closure was achieved in 54 (98%) and 60 (97%) eyes in the flap and peel groups, respectively.

--The preoperative and postoperative 12-month BCVA were comparable between the groups but were significantly better in the flap than in the peel groups at 1 month, 3 months, and 6 months.

--In the flap group, foveal gliosis was less common than the peel group at 1 month and restored external limiting membrane and interdigitation zone was more common at 3 months.

Conclusively, both the single-layer ILM flap and the traditional ILM peel approaches enhanced eyesight by closing FTMHs. ILM flaps have been linked to superior visual results for up to 6 months after surgery and should be explored in FTMHs less than 400 micro-m.