Sister Mary Joseph Nodule as a First Manifestation of a Meta
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Sister Mary Joseph nodule (SMJN) is a rare umbilical lesion resulting from an intra-abdominal and/or pelvic malignancy. It was named after Sister Mary Joseph, a surgical assistant to Dr. William J. Mayo, who noted the association between the presence of an umbilical nodule and an intra-abdominal malignancy. Its incidence is 1%–3% of all intra-abdominal or pelvic malignancies. Gastrointestinal malignancies, most commonly gastric, colon, and pancreatic, account for about 52% of cases and gynecological cancers, most commonly ovarian and uterine account for about 28% of the underlying sources.Here, we present a case of SMJN as an ovarian cancer metastasis, its diagnosis, treatment and follow-up....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007344/
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