Spontaneous involution of a Rathke's Cleft Cyst in a patient
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Rathke cleft cyst is described as a benign intrasellar cyst. They are mostly small and asymptomatic; they may become large enough to cause symptoms by compression of intrasellar or suprasellar structures. We report a case of spontaneous regression of a symptomatic RCC with subsequent recovery of pre-existing endocrine dysfunction and resolution of headaches. A 60-year-old man complained of headaches. Laboratory investigation revealed a partial hypopituitarism with a slight central hypothyroidism without the need for substitution. An MRI study showed a cystic, T2-hyperintense, sellar lesion compatible with an RCC. At one year follow-up, the patient had no complaints and the hormone work-up revealed a regression of the previous slight hypopituitarism. The MRI study showed a complete regression of the cystic lesion and a normal sized and shaped pituitary gland.

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