Squamous Cell Carcinoma Arising in a Mature Cystic Teratoma
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Case
A perimenopausal 52-year-old woman, gravida 3, para3, was admitted by our clinic in April 2012 with a one-month history of vaginal bleeding and progressive abdominal discomfort. She dose not have known medical history, medication, drinking alcohol problem, and family history of cancer. The patient's gynecologic examination and transvaginal ultrasound showed a mass in the right adnexa. Moreover, pelvic magnetic resonance imaging showed mass of about 7?cm in diameter in the right adnexal with coexisting cystic and solid densities. In the Doppler screening, there was a vascularization in solid component, and the value of the Resistance Index (RI) at Doppler scan was 0.71. Serum levels of cancer antigen are CA-125: 57?U/mL (<35). Colonoscopy was normal. Abdominal tomography and pelvic magnetic resonance imaging were negative for any metastasis. The patient underwent total abdominal hysterectomy with bilateral oophorectomy, omentectomy, pelvic lymph node dissection and debulking. Grossly an opened uniloculated cystic mass was received measuring 12 × 7.5?cm in size with 0.2?cm wall thickness. The cyst wall contained a mural nodule measuring 7 × 7 × 2?cm in size. Intraoperative pathology consultation revealed a malignant epithelial tumor consistent with squamous cell carcinoma arising in a mature cystic teratoma.....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540696/
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