Squamous Cell Carcinoma of the Anal Transitional Zone after
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Squamous cell carcinoma (SCC) after ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) is very rare. SCC is extremely sensitive to chemoradiation therapy (CRT), but an ileal pouch is generally considered a contraindication to radiotherapy. No validated guidelines exist on how to treat SCC after IPAA.Few cases of SCC in IPAA patients have been described in the literature, with variable treatments and unpredictable outcomes. We report the successful management of an SCC of the anal transitional zone (ATZ) after IPAA and systematically review the literature for IPAA-related SCC....

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