Benefit of Early Revascularization Based on Inducible Ischemia and Left Ventricular Ejection Fraction
The utility of performing early myocardial revascularization among patients presenting with inducible myocardial ischemia and low left ventricular ejeâ?¦
Researchers evaluated 43,443 patients undergoing a stress-rest single-photon emission computed tomography myocardial perfusion imaging. The median follow-up was 11.4 years. Myocardial ischemia was assessed for its interaction between early revascularization and mortality. The frequency of myocardial ischemia varied markedly according to LVEF and angina, ranging from 6.7% among patients with LVEF 55% and no typical angina to 64.0% among patients with LVEF <45% and typical angina (P < 0.001). Among 39,883 patients with LVEF 45%, early revascularization was associated with increased mortality risk among patients without ischemia and lower mortality risk among patients with severe (15%) ischemia. Among 3,560 patients with LVEF <45%, revascularization was not associated with mortality benefit among patients with no or mild ischemia and was associated with decreased mortality among patients with moderate (10%-14%) and severe (15%) ischemia.
Source: https://www.sciencedirect.com/science/article/abs/pii/S0735109722050392
Source: https://www.sciencedirect.com/science/article/abs/pii/S0735109722050392
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