Study: Developmental Improvement in Children with Intellectu
A Study was conducted to assess the impact of refractive error correction from photorefractive keratectomy on development in children with severe isoametropia, subnormal visual acuity and intellectual disability unable to use refraction correction.

Before and after PRK, subjects who had plateaued developmentally for 18+ months were assessed using a battery of developmental tests. The primary outcome measure was the change in the developmental quotient (DQ) 6 months after PRK. Secondary outcomes were the change in the DQ, uncorrected visual acuity, cycloplegic refraction and corneal status 12, 24, and 36 months after PRK.

--16 subjects aged 2-8 years were included. 12 were highly myopic, three highly hyperopic and one highly astigmatic.

--6 months post-PRK, the DQ significantly improved for expressive communication, interpersonal relationships and coping.

--12 months post-PRK, the DQ significantly improved for receptive communication, expressive communication, written communication, domestic skills, interpersonal relationships, and coping.

Finally, PRK improves developmental capacities in children with intellectual disabilities, severe isoametropia, and previously plateaued development, as well as visual acuity and refractive error.