Study Finds A Link Between Antihypertensive Drugs And Psoria
A study found a link between use of antihypertensive medications and the development of psoriasis. The study indicated that angiotensin-converting-enzyme inhibitors, beta- blockers, calcium-channel blockers, and thiazide diuretics may increase the risk of psoriasis. The researchers analyzed databases and included 13 eligible studies for meta analysis and 8 for network meta-analysis. Results showed that all antihypertensive drugs were significantly associated with psoriasis incidence. In a meta-analysis, the pooled ORs were 1.67 for angiotensin-converting enzyme (ACE) inhibitors, 1.40 for beta-blockers, 1.53 for calcium-channel blockers (CCBs), and 1.70 for thiazide diuretics. For the comparative risks of psoriasis among antihypertensive drugs in the network meta-analysis, ORs were 2.09 for ACE inhibitors, 1.35 for BBs, 1.53 for CCBs and 1.80 for thiazide diuretics. This study confirmed the associations between antihypertensive drugs and psoriasis. Therefore, antihypertensive drug users should be carefully monitored for psoriasis.

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https://doi.org/10.1111/bcp.15060
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