Study Finds, Association between Esophageal Atresia and Resp
A Study was conducted to identify the factors associated with readmissions for respiratory causes in the first year in esophageal atresia (EA) children. Respiratory diseases are common in children with (EA), leading to increased morbidity and mortality in the first year.

Researchers included all children born with available data and analyzed factors at birth and 1 year follow-up.

Results:
--Among 1460 patients born with EA, 97 (7%) were deceased before the age of 1 year, and follow-up data were available for 1287 patients, who constituted our study population.

--EAs were Ladd classification type III or IV in 89%, preterm birth was observed in 38%, and associated malformations were observed in 52%.

--Collectively, 61% were readmitted after initial discharge in the first year, 31% for a respiratory cause.

--Among these, respiratory infections occurred in 64%, and 35% received a respiratory treatment.

--In logistic regression models, factors associated with readmission for a respiratory cause were recurrence of tracheoesophageal fistula, aortopexy, antireflux surgery, and tube feeding; factors associated with respiratory treatment were male sex and laryngeal cleft.

Conclusively, respiratory morbidity is common in the first year following EA repair, accounting for more than half of readmissions. Identifying high-risk groups of EA patients (those with chronic aspiration, respiratory abnormalities, and tube feeding) could help guide follow-up efforts.

Source: https://pediatrics.aappublications.org/content/148/3/e2020049778?rss=1
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