Study Finds Link Between Contraceptive Pills, T2D and PCOS
A study claimed that contraceptive pills can reduce the risk of type 2 diabetes by over a quarter in women with polycystic ovary syndrome. Team of scientists carried out two studies; firstly to identify the risk of developing type 2 diabetes and pre-diabetes in women with PCOS, and secondly to investigate the impact of the use of combined oral contraceptives on the risk of type 2 diabetes and pre-diabetes in women with PCOS. They used records of 64,051 women with PCOS and 123,545 matched control women without PCOS and they first carried out a large population-based cohort study to analyse the risk of type 2 diabetes and pre-diabetes. The findings showed that women with PCOS were twice at risk of type 2 diabetes or pre-diabetes, compared to those without PCOS. Further, to investigate the impact of the pill on type 2 diabetes or pre-diabetes,they then carried out a nested case-control study of 4,814 women with PCOS. The scientists found that the use of combined oral contraceptives reduced the odds of developing type 2 diabetes and pre-diabetes in women with PCOS by 26%. The researchers behind the study are now planning to carry out a clinical trial to further evidence their findings in the hope it will lead to changes in global healthcare policy.

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https://doi.org/10.2337/dc21-0437
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