Study, Gait Risk Factors for Disease Progression in Non-trau
A Study was conducted to examine if relationships between knee osteoarthritis (OA) progression with knee moments and muscle activation during gait vary between patients with non-traumatic and post-traumatic knee OA.

Researchers included participants with non-traumatic (n=17) and post-traumatic (n=18) knee OA; the latter group had a previous anterior cruciate ligament rupture. Motion capture cameras, force plates, and surface electromyography measured knee moments and lower extremity muscle activation during gait. Cartilage volume change were determined over 2 years using magnetic resonance imaging in four regions: medial and lateral plateau and condyle.

--Measures from knee adduction and rotation moments were related to lateral condyle cartilage loss in both groups, and knee adduction moment to lateral plateau cartilage loss in the non-traumatic group only.

--Generally, lower levels of stance phase muscle activation were related to greater cartilage loss.

--The relationship between cartilage loss in some regions with muscle activation characteristics varied between non-traumatic and post-traumatic groups including for: lateral hamstring, rectus femoris, and medial hamstrings.

Finally, the findings suggest that gait risk factors for OA progression differ between non-traumatic and post-traumatic knee OA patients. In research looking into gait measurements as risk factors for OA progression, these OA subtypes should be taken into account.