Study: Macular sensitivity assessment and fixation analysis
A Study was conducted to investigate the retinal sensitivity and fixation stability using microperimetry in children with retinopathy of prematurity (ROP).

Totally 51 preterm children who had been followed for ROP were examined in three groups (n=17 in each group). The groups were defined as children without ROP (group 1), children with spontaneously resolved ROP (group 2) and children who had laser treatment for ROP (group 3). All subjects underwent a detailed ophthalmic examination.

Macular Analyzer Integrity Assessment Microperimetry was used to analyse macular light sensitivity and fixation stability. The results were compared between groups. The measurements were also analysed according to age, gender, birth weight and gestational age.

Results:
--The mean age was 10.84±0.97 years, and 27 children were female. Mean average threshold (AT) for macular sensitivity was 25.5±2.1 decibel in group 1, 26.8±3.8 decibel in group 2 and 26.3±3.0 decibel in group 3.

--These differences were not statistically significant between the groups, but AT was abnormal in 29% of the whole study population.

--Outputs about fixation stability were similar between the three groups but fixation was unstable in 27% of the subjects.

--Mean AT was better in children more than 11 years old compared with the younger ones.

Preterm children may end up with some abnormality in the sensitivity to macular light and stabilization. In youngsters under the age of 11 these anomalies may be more obvious. ROP itself or the laser treatment does not appear to impair the sensitivity and stability of macular light.

Source: https://bjo.bmj.com/content/early/2021/06/08/bjophthalmol-2021-319352?rss=1
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