Study, Photoreceptor Outer segment layer contributes to OCT
A Study was conducted to establish the factors responsible for attenuation of the optical coherence tomography (OCT) signal beneath the neurosensory detachment (NSD).

Researchers retrospectively reviewed 33 eyes with acute central serous chorioretinopathy. The thickness of the neurosensory retina, the thickness of the photoreceptor outer segment (PROS) layer, the height of the NSD, and the reflectivity of the underlying retinal pigment epithelium (RPE) were measured at selected points of B-scans exported from 6×6mm OCT angiography protocols.

The intensity of the flow signal was measured at the corresponding regions of the choriocapillaris slab. The correlation between the parameters of the NSD and both the reflectivity of underlying RPE and the intensity of the flow signal in the choriocapillaris was calculated.

Results:
--Correlation coefficients between RPE reflectivity and neurosensory retinal thickness, PROS layer thickness, and NSD height were 0.32, 0.64, and 0.25, respectively.

--Correlation coefficients between the intensity of the flow signal and neurosensory retinal thickness, PROS layer thickness, and NSD height were 0.24, 0.52, and 0.13 respectively.

The thickness of the PROS layer, in particular, is the most important element influencing OCT signal at the level of RPE and OCT angiography flow signal in the choriocapillaris beneath the NSD.

Source: https://www.nature.com/articles/s41433-021-01736-2?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed:+eye/rss/current+(Eye+-+Issue)
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