Study: Respiratory system findings in Pediatric patients wit
The aim of this study is to assess the pulmonary system of the pediatric patients with PID and report the demographical, clinical, and radiological findings regarding the underlying PID.

The present study included pediatric patients who were receiving immunoglobulin replacement therapy (IGRT) for PID.

--A total of 48 patients, aged 9.9 years were included. Time of delay in the diagnosis of immundeficiency was 2.27 years. CVID patients exhibited higher respiratory system symptoms, as well as a history of recurrent lung infection and hospitalization.

--Hilar and mediastinal lymphadenopathies, peribronchial thickening, and bronchiectasis were the most common pulmonary complications and more than three lung lobes were affected in 69%.

--Among the newly diagnosed patients, bronchiectasis was present in 25% and more than three lobes were affected in 62.5%.

--Although pulmonary nodules and mediastinal lymphadenopathy were frequently computed tomography findings in these patients, only 2 patients were diagnosed with interstitial lung disease.

Conclusively, Although bronchiectasis is predominantly reported as a long-term complication in adult patients with PID, half of the pediatric patient cohort with PID had bronchiectasis, even the newly diagnosed patients.