Study finds, Continued Increase of Axial Length and Its Risk
A Study was conducted to determine the risk factors associated with axial elongation in adults with high myopia.

This cohort study used the medical records of 43201 patient. A total of 15 745 medical records with the patients’ sex, best-corrected visual acuity (BCVA), axial length, type of myopic maculopathy, and the presence or absence of choroidal neovascularization (CNV) were reviewed.

Results:
--Among 1877 patients with 9161 visits included in the analysis, the mean (SD) age was 62.10 years, and 1357 were women.

--The mean (SD) axial length was 29.66 mm with a mean (SD) growth rate of 0.05 mm/y.

--Among the 9161 visits, 7096 eyes had myopic maculopathy and 2477 eyes had CNV.

--The odds ratio for inducing a severe elongation of the axial length was 1.46 for female sex, 0.44 to 0.63 for older than 40 years, 1.33 for BCVA of less than 20/400, 1.67 to 2.67 for baseline axial length of 28.15 mm or greater, 1.06 to 1.39 for the presence of maculopathy, and 1.37 for prior CNV.

In conclusion, this cohort study discovered that people with extreme myopia have continued axial elongation. Because the risk factors for elongation do not appear to be changeable, prevention of pathologic myopia and its consequences may be the best strategy for lowering the occurrence of pathologic myopia and its complications in the future

Source: https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2783396
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