Study finds, Disc Hemorrhages are Associated with Localized
A Study was conducted to evaluate the relationship between the occurrence of optic disc hemorrhages (DH) and glaucoma progression as determined by multiple glaucoma testing modalities.

A longitudinal study conducted on the same day over a 5-year term in 124 open-angle glaucoma patients with yearly disc photography (DP), visual fields (VF's), retinal nerve fiber (RDNF), and optic nerve volume scans,  spectral-domain optical coherence tomography (SD-OCT) retinal nerve fiber layer (RNFL) thickness scans. From scans of the optical nerve volume, the minimum distance band (MDB), a 3D neuroretinal rim parameter, was derived. The patients used event-based analysis were classified as progressives in glaucoma or non-glaucoma.

--Out of 124 open angle glaucoma patients, 19 had one or more DHs on yearly DPs.

--Presence of a DH was associated with localized 3D neuroretinal rim thickness progression (superior MDB progression; OR 3.96), but not with global or inferior MDB progression, DP progression, VF progression, or RNFL global, inferior or superior progression.

--In the majority of patients with MDB progression (14/17, or 82%), the progression was noted before or concurrently with the first instance of DH.

Conclusively, 3D SD-OCT neuroretinal rim measures of glaucoma progression found in the majority of patients preceded the DH incidence. These results supports the concept that DHs are indications of advancement of glaucoma rather than distinct events that cause progression.