Study finds, Effect of blue light-filtering IOLs on age-rela
A Study was conducted to estimate the incidence rate of age-related macular degeneration (AMD) after cataract surgery and to compare the relative incidence of AMD in pseudophakes with blue light-filtering intraocular lenses (BF-IOLs) and non-BF-IOLs.

186,591 patients who underwent cataract surgery in both eyes were enrolled and followed them from the index date. Propensity score matching (PSM) was used to balance the baseline characteristics between the two IOL groups, namely BF-IOL and non-BF-IOL groups.

Results:
--In total, 21,126 and 165,465 patients had BF-IOL and non-BF-IOL implants, respectively.

--Patients in the BF-IOL group tended to be younger, with fewer males, different cataract surgery years, higher income, more non-manual workers, more patients from urban and suburban areas, and fewer chronic diseases compared to the non-BF-IOL group.

--With a mean follow-up period of 6.1 years after cataract surgery, 12,533 and 1,655 patients developed non-exudative AMD and exudative AMD, respectively.

--The incidence rate of non-exudative AMD and exudative AMD was 9.95 and 1.22 for the BF-IOL group, and 11.13 and 1.44 for the non-BF-IOL group, respectively.

--After PSM, no statistical difference in the incidence rate of non-exudative AMD and exudative AMD was observed between the two IOL groups.

Finally, after cataract surgery, the incidence rate of AMD was 11.59 per 1000 person-years. The usage of a BF-IOL for up to ten years provided no discernible benefit over non-BF-IOL in terms of AMD incidence.

Source: https://www.ajo.com/article/S0002-9394(21)00403-7/fulltext?rss=yes
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