Study finds, Effect of internal limiting membrane peel for i
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
This Study aimed to compare the functional and anatomical outcomes after epiretinal membrane (ERM) peeling with internal limiting membrane peeling (ERM/ILM) and without (ERM) for the treatment for idiopathic ERM.

A comprehensive search for randomized controlled trials comparing ERM/ILM and ERM was performed. Methodological quality was assessed using the Cochrane Risk of Bias tool. Quality of body of evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.

Results:
--7 studies reporting 387 eyes overall were included. 207 received ERM/ILM. 180 received ERM.

--Post-operative visual acuity was not significantly different between ERM/ILM and ERM with a mean difference (MD) of 0.02 at 1 month, 0.03 at 3 months, 0.01 at 6 months, and 0.01 at 12 months post-operatively.

--ERM/ILM was significantly associated with lower ERM recurrence at 6-12 months with a relative risk of 0.16 and an increased central macular thickness (microns) at 12 months with MD of 20.53.

In conclusion, despite minor anatomical variations, ERM/ILM and ERM produce identical visual acuity (central macular thickness). ERM/ILM is linked to a slightly lower risk of ERM recurrence 6-12 months after surgery, which should be considered when recurrence prevention is a primary concern.

Source: https://www.sciencedirect.com/science/article/abs/pii/S0002939421002270?dgcid=rss_sd_all
Like
Comment
Share