Study finds, Effects of Internal limiting membrane peeling d
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
A Study was conducted to evaluate the benefits of internal limiting membrane peeling in proliferative diabetic retinopathy subjects undergoing pars plana vitrectomy for the treatment of vitreous hemorrhage.

258 proliferative diabetic retinopathy subjects undergoing pars plana vitrectomy for vitreous hemorrhage were enrolled into the trial. Patients were randomized into one of two cohorts: Group A patients underwent internal limiting membrane peeling, whereas Group B patients did not undergo internal limiting membrane peeling.

The main outcome was best-corrected visual acuity at 6 months. Secondary outcomes were optical coherence tomography central macular thickness at 6 months, incidence of diabetic macular edema treatment during the postoperative trial period, and incidence of epiretinal membrane at 6 months.

Results:
--207 patients were randomized and completed 6 months follow-up.

--Group A had better best-corrected visual acuity at 6 months than Group B.

--Group A had a lower incidence of diabetic macular edema treatment during the postoperative trial period and a lower incidence of epiretinal membrane at 6 months than Group B.

--There was a trend toward lower central macular thickness on optical coherence tomography in Group A than Group B.

--There were no significant differences in baseline details or complications intraoperatively or postoperatively between cohorts.

In conclusion, when internal limiting membrane peeling was done, this trial showed improved vision, less postoperative diabetic macular edema treatments, and a lower occurrence of epiretinal membrane at 6 months. In proliferative diabetic retinopathy patients undergoing pars plana vitrectomy for vitreous hemorrhage, internal limiting membrane peeling can be a critical maneuver to conduct.

Source: https://journals.lww.com/retinajournal/Abstract/2021/05000/INTERNAL_LIMITING_MEMBRANE_PEELING_DURING.28.aspx
Like
Comment
Share