Study finds, Effects of Varying Illumination on Ocular Aberr
A Study was conducted to evaluate the changes in refraction, higher-order aberrations, and aberration compensation between mesopic and photopic illumination before and after small incision lenticule extraction.

In this study, only the right eyes of patients who underwent small incision lenticule extraction for the correction of myopia and myopic astigmatism were included. Wavefront refraction and higher-order aberrations were measured preoperatively and 3?months postoperatively under mesopic and photopic illumination.

Results:
--40 patients undergoing small incision lenticule extraction were enrolled. All surgeries were completed without postoperative complications.

--Preoperatively, the eyes only had a statistically significantly higher spherical refractive error under mesopic vs. photopic illumination, whereas postoperatively, the eyes also exhibited statistically significantly higher astigmatism.

--Differences in spherical refraction between the two illuminations were the highest in postoperative eyes.

--Only postoperative eyes exhibited statistically significant elevations in higher-order aberrations under mesopic illumination, and only preoperative eyes exhibited statistically significantly enhanced and decreased compensation factors under mesopic illumination.

Conclusively, under mesopic illumination, exaggerations in higher-order aberrations and myopic shift after tiny incision lenticule extraction were visible. Under low illumination, slight undercorrection may enhance the impression while reducing night vision. Under mesopic illumination, the unique modifications in compensatory effects in preoperative eyes may improve optical quality. Under mesopic illumination, postoperative eyes have impaired compensatory ability, particularly for spherical aberrations, which may reduce night vision.

Source: https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-021-02084-1
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