Study finds, Efficacy of Gabapentin for managing pain in Chi
Gabapentin is often used to manage pain in children with dystonic cerebral palsy. The primary objective of this feasibility pilot study was to assess the factors which might impact on a future randomised controlled trial including the ability to recruit and retain participants, assess adherence/compliance to the prescribed intervention, and ability to complete all outcome assessments.

This open label pilot study recruited children aged 5–18 years with dystonic cerebral palsy and accompanying pain affecting daily activities. Children were prescribed gabapentin for 12 weeks and were assessed at baseline, 6 weeks and 12 weeks. The primary outcome was feasibility of the protocol. Secondary outcomes were pain behaviour, pain intensity, care and comfort, individualised goal setting and dystonia severity.

--13 children were recruited from 71 screened over 15 months. --2 children withdrew while 8 children experienced side effects. There were issues with adherence to medication dosage regimens and data collection.
--Improvements were seen in pain behaviour, comfort and pain related goals at 12 weeks. Dystonia was not significantly changed.

To summarize, while gabapentin may help pain and comfort in children with dystonic CP, the feasibility of conducting a conclusive randomized controlled trial is minimal.