Study finds, Impact of myopia on the association of long-ter
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A Study was conducted to investigate whether the association of long-term intraocular pressure (IOP) fluctuation with the rate of progression of normal-tension glaucoma (NTG) differs between myopia and non-myopia.

Medical reports were checked for 65 myopic NTG eyes (axial length (AL) greater than 24.0 mm) and 64 non-myopic NTG eyes (AL less than 24.0 mm) that had been treated with topical medications for more than 5 years. The relationships of the slope of mean deviation (MD) or visual field index (VFI) with clinical variables, including interactions with myopia, were investigated using several linear regression models.

Results:
--The average follow-up period was 8.3 years.
--22 non-myopic eyes and 27 myopic eyes showed NTG progression.
--The interaction of myopia with IOP fluctuation was a significant factor regarding both MD and VFI slope; stratified analyses suggested that the risk effect of IOP fluctuation was significant only in myopic NTG in terms of both MD (beta= ?1.27) and VFI slope (beta=?2.32).

Finally, relative to non-myopic NTG eyes, long-term IOP fluctuation was significantly linked to faster visual field progression in myopic NTG eyes.

Source: https://bjo.bmj.com/content/105/5/653?rss=1
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