Study finds, Incidence of paediatric eosinophilic esophagiti
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The rate of eosinophilic esophagitis (EoE) diagnosis is increasing. This study aims to determine the incidence of EoE in the paediatric population residing in the southwestern Madrid and to analyse whether absolute monthly pollen counts, modified or not by the principal atmospheric pollutants, are associated with it.

The prevalence of EoE in children under the age of 15 was calculated using a cross-sectional analysis of prospectively recruited patients. Each patient's demographic and symptom data, as well as the date of onset of symptoms, date of medical appointment, and date of endoscopic diagnosis, were collected.

Relative risk estimation was performed to assess the association between the incidence of diagnosis and monthly pollen counts and levels of atmospheric pollutants. All these models were adjusted for the number of total patients that underwent endoscopy at first-time.

Results:
148 patients were included. The most frequent symptoms were abdominal pain [42.57%], dysphagia [42.57%] and impaction [39.86%].

--The median overall monthly incidence was 1.13 cases/100,000 children and the annual mean was 15.2.

--The overall analysis of the relationship between incidence and absolute monthly counts, corrected for the number of first-time endoscopies performed, revealed no statistically significant association with pollen and air pollutants.

--There was a higher frequency of diagnosis during the pollination period of Cupressaceae [Relative Risk 1.647] and during February and November (relative risk 1.67).

In conclusion, this study confirms the high incidence of eosinophilic esophagitis and also indicates that the months of February and November, as well as the time of high pollination of Cupressaceae, are associated with a higher incidence of diagnosis.

Source: https://onlinelibrary.wiley.com/doi/10.1111/pai.13528?af=R
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