Study finds, Increased Medical Complications following Prima
The purpose of this study was to compare 90-day postoperative complications and 2-year surgical complications following primary THA in patients with and without a history of SOT. As patient longevity increases following solid organ transplant (SOT), more transplant patients are undergoing total hip arthroplasty (THA).

Patients with a history of SOT with subsequent primary THA were identified. This SOT cohort was propensity-matched with a control cohort based on age, gender, Charlson Comorbidity Index (CCI), and obesity with bivariate analysis to compare outcomes between cohorts.

--Following matching, 3,103 patients were included in the SOT cohort and 6,196 patients in the control cohort.

--The cohorts were successfully matched, with no differences in demographics or comorbidities.

--Relative to the control cohort, patients with a history of SOT were at significantly increased risk of renal failure, anemia, arrhythmia with and without atrial fibrillation, blood transfusion, cellulitis, myocardial infarction, pneumonia, heart failure, and sepsis at 90 days postoperatively.

--There were no significant differences between the cohorts in two-year surgical complications or revisions, which included indications of periprosthetic joint infection (PJI) and instability.

Those with a history of SOT have a higher risk of 90-day medical issues, but not two-year surgical complications or revisions, than patients without SOT after primary THA. When advising and managing this patient population, clinicians should be aware of the elevated risk of cardiac, renal, hematologic, and infectious problems.