Study finds, Influence of Retinal oxygen saturation and Chor
Researchers aimed to investigate the effects of vitrectomy (Vy) with or without same time cataract surgery and membrane plus internal limiting membrane peeling (MP+ILMP) on retinal oxygenation and choroidal volume and their role on postoperative outcome.

32 eyes were included in this prospective clinical study. All patients received 23 gauge Vy+MP+ILMP. Additional cataract surgery was performed in 14 patients. Follow-up visits were scheduled at day 1, week 1, month 1 and month 3. At each visit, best corrected visual acuity (BCVA) using ETDRS charts, oxygenation of retinal vessels using the Oxymap T1, and optical coherence tomography was performed.

--Mean BCVA increased significantly from 73 ± 11 letters to 77 ± 7 letters at month 3. Mean central retinal thickness (CRT) decreased from 456 ± 84 microm at baseline to 418±58 microm.

--In the cataract surgery group, CRT was higher at month 3 than in the group without.

--There was no statistically significant difference in choroidal volume or oxygenation of retinal vessels between groups.

--Oxygenation of retinal arteries tended to decrease at day 1 followed by an increase, but the changes did not reach the level of significance.

--Oxygenation of retinal veins increased significantly. There was a significant negative correlation between visual acuity and oxygenation of retinal veins at month 3.

--No statistically significant correlation was found between CRT and oxygenation of neither retinal arteries nor veins. Choroidal volume (CV) of the central mm did not change significantly during the study period.

--There was no statistically significant effect of choroidal volume at baseline on postoperative clinical outcomes.

Conclusively, Oxygen saturation may affect the visual acuity outcome but not the CRT in patients after vitrectomy for epiretinal membrane.