Study finds, Long-Term Outcomes of Combined Photorefractive
A Study was conducted to present the long-term outcomes of photorefractive keratectomy (PRK) combined with accelerated corneal cross-linking (CXL) for refractive error correction in a series of keratoconus suspects.

A series of patients with topographic findings suspicious for keratoconus underwent simultaneous PRK and prophylactic accelerated CXL (5 minutes with intensity of 18 mW/cm2) for the correction of their refractive error. The results were recorded for more than 4 years postoperatively.

--10 eyes of 5 patients were included. Mean follow-up was 58.2 months. Mean age at presentation was 25 years. Mean spherical equivalent (SE) refraction was -2.76.

--At last, follow-up 9 out of 10 eyes had SE refraction within ± 0.50D and all eyes had SE within ± 1.00D.

--None of the eyes lost any line of corrected distance visual acuity (CDVA), whereas 1 eye gained one line of CDVA.

--All eyes demonstrated stability of their results during the follow-up period.

Simultaneous PRK followed by prophylactic accelerated CXL (PRK plus) appeared, in this series of patients suspected of keratoconus, to be a safe, effective choice for correction of the refractive defect without compromising corneal stability up to a 5 year post-operatively.