Study finds, Multisite Pain is Highly Prevalent in Children
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A Study was conducted to characterize the types of multisite pain experienced by children with functional abdominal pain disorders (FAPDs) and to examine differences in psychosocial distress, functional disability and health-related quality of life in children with multisite pain vs. abdominal pain alone.

Children with pediatric Rome III FAPDs (n=406) were recruited for a cross-sectional analysis. The participants filled out 14-day pain and stool diaries, as well as validated questionnaires on abdominal and non-abdominal pain symptoms, anxiety, depression, functional impairment, and health-related quality of life.

Results:
--295 children endorsed at least one co-occurring non-abdominal pain thus were categorized as having multisite pain with the following symptoms: 172 headaches, 143 chest pain, 134 muscle soreness, 110 back pain, 94 joint pain, and 87 extremity (arms and legs) pain.

--In addition, 200 children endorsed two or more non-abdominal pain symptoms.

--Participants with (vs without) multisite pain had significantly higher abdominal pain frequency and severity, anxiety, and depression.

--Similarly, children with multisite pain (vs. without) had significantly worse functional disability and health-related quality of life scores.

--Increasing number of multisite pain sites was associated with increased functional disability when controlling for demographic and other clinical factors.

Finally, non-abdominal multisite pain is common in children with FAPDs and is linked to increased psychosocial distress, abdominal pain frequency and intensity, physical impairment, and a lower health-related quality of life.

Source: https://www.jpeds.com/article/S0022-3476(21)00411-X/fulltext?rss=yes
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