Study finds, Muscle strength and Osteoarthritis progression
A Study was conducted to evaluate the muscle strength changes following partial meniscectomy or exercise therapy for degenerative meniscal tears and the relationship between baseline muscle strength and osteoarthritis progression.

Secondary analysis of a randomized trial (n=140 participants) was done. Isokinetic quadriceps and hamstrings strength were assessed at baseline, 3-, 12-month, and 5-year follow-up. Between-group differences were analyzed using intention-to-treat linear mixed models. The relationship between baseline muscle strength and osteoarthritis progression were assessed using logistic regression models.

Results:
--Researchers found statistically significant between-group differences favoring exercise therapy at three months.

--At five years, between-group differences were -0.10 N·m/kg for quadriceps and -0.07 N·m/kg for hamstrings.

--Quadriceps muscle weakness at baseline was associated with knee osteoarthritis progression over five years: adjusted odds ratio of 1.40 for every 0.2 N·m/kg decrease.

--The adjusted odds ratio for hamstrings was 1.14 for every 0.1 N·m/kg decrease.

In the end, exercise therapy has been successful at improving muscle strength for 3 and 12 months compared with partial meniscectomy, but its benefit has been reduced by five years. Quadriceps baseline muscular weakening was connected with the increased probability of osteoarthritis after five years.

Source: https://onlinelibrary.wiley.com/doi/10.1002/acr.24736?af=R
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