Study finds, Prevalence of Ocular Demodicosis in an Older Po
A Study was conducted to evaluate the association between Demodex and its symptoms and ocular surface parameters in individuals with dry eye (DE).

A cross-sectional study of 119 individuals with DE symptoms or signs, grouped by the presence of ocular demodicosis, was performed. Demographics, comorbidities, symptoms profiles, and ocular surface parameters were compared between the 2 groups. Receiver operating curves analysis were performed to evaluate relationships between Demodex quantity and specific clinical phenotypes.

Results:
--Demodex was highly prevalent in our population (68.9%) with average counts of 4.2 ± 3.9. Individuals with and without Demodex had comparable demographics.

--Overall, symptoms profiles were similar between individuals with and without Demodex using the Dry Eye Questionnaire 5 and Ocular Surface Disease Index.

--Individuals with Demodex, however, were more likely to report itching (58.5% vs. 35.1%), with increasing frequency in those with higher Demodex counts.

--Individuals with Demodex also had more severe eyelid abnormalities and a more unstable tear film but similar tear production and corneal staining when compared with individuals without Demodex.

-- Receiver operating curves analysis revealed Demodex counts more than 2 maximized sensitivity and specificity for both itching (64.7% and 59.0%, respectively) and CD (80.4% and 60.4%, respectively).

Demodex is more prevalent in an elderly population with DE. The most specific findings for Demodex were itching symptoms and CD.

Source: https://journals.lww.com/corneajrnl/Abstract/2021/08000/Prevalence_of_Ocular_Demodicosis_in_an_Older.10.aspx
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