Study finds, Prevalence of Ultrasound-detected knee synovial
Researchers examined the prevalence of synovial abnormalities on ultrasound and the relationship of these features with knee pain and radiographic osteoarthritis (ROA) in a community sample.

Participants aged 50 years or over were included in the cohort study. Participants were questioned about chronic knee pain and they underwent (1) Ultrasonography of both knees to determine presence of synovial hypertrophy (more than 4 mm), effusion (more than 4 mm), and Power Doppler signal [PDS; yes/no]; and (2) Standard radiographs of both knees (tibiofemoral and patellofemoral views) to determine ROA.

Results:
--There were 3755 participants. The prevalence of synovial hypertrophy, effusion, and PDS were 18.1%, 46.6%, and 4.9%, respectively, and increased with age.

--Synovial abnormalities were associated with knee pain, with adjusted odds ratios (aORs) of 2.39 for synovial hypertrophy, 1.58 for effusion, and 4.36 for PDS.

--Similar associations with ROA were observed, the corresponding aORs being 4.03, 2.01, and 6.49, respectively.

--The associations between synovial hypertrophy and effusion with knee pain were more pronounced among knees with ROA than those without ROA, and the corresponding P for interaction were 0.004 and 0.067, respectively.

Knee synovial hypertrophy and effusion are, in conclusion, more common and age-intensive and affect men than women. Each of the three synovial abnormalities observed in ultrasounds involves both knee pain and ROA and synovial knee hypertrophy or effusion. ROA can combine to raise the likelihood of knee suffering.

Source: https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-021-02539-2
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