Study finds Progression of Lung Ultrasound Score in Neonatal
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The utility of a lung ultrasound score (LUS) has been described in the early phases of neonatal respiratory distress syndrome (RDS). Researchers investigated lung ultrasound as a tool to monitor respiratory status in preterm neonates throughout the course of RDS.

Preterm neonates, stratified in 3 gestational age cohorts (25–27, 28–30, and 31–33 weeks), underwent lung ultrasound at weekly intervals from birth. Clinical data, respiratory support variables, and major complications (sepsis, patent ductus arteriosus, pneumothorax, and persistent pulmonary hypertension of the neonate) were also recorded. In total 240 infants were enrolled.

Results:
--The 3 gestational age intervals had significantly different LUS patterns.

--There was a significant correlation between LUS and the ratio of oxygen saturation to inspired oxygen throughout the admission, increasing with gestational age (b = -0.002 at 25–27 weeks; b = -0.006 at 28–30 weeks; b = -0.012 at 31–33 weeks).

--Infants with complications had a higher LUS already at birth (12 interquartile range 13–8 vs 8 interquartile range 12–4 control group).

--In infants 25 to 30 weeks gestation, the LUS at 7 days of life predicted bronchopulmonary dysplasia with an area under the curve of 0.82.

Finally, the LUS trajectory is gestational age dependent, substantially correlates with oxygenation status, and predicts bronchopulmonary dysplasia in preterm neonates with RDS. LUS is a useful, noninvasive, bedside method for monitoring respiratory status in this population.

Source: https://pediatrics.aappublications.org/content/early/2021/03/05/peds.2020-030528?rss=1
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