Study finds, Relationship Between Magnetic Resonance Imaging
A Study was conducted to explore whether magnetic resonance imaging (MRI) features suggestive of knee osteoarthritis (OA) are associated with presence of knee pain in possible early-stage OA development.

294 participants were included from the Osteoarthritis Initiative with baseline Kellgren/Lawrence grade of 0 in both knees, all of whom had received knee MRIs at 4 different time points over 6 years. Using a linear mixed model, researchers studied whether MRI features were associated with knee-specific pain as reported on the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire using a 0–100 scale (worst to best).

--The differences in KOOS knee pain score for a knee with a 1 unit higher score on MRI were the following: meniscal extrusion –1.5; cartilage area loss –0.23; cartilage full thickness loss –1.04; osteophytes –0.32; meniscal integrity –0.28; BMLs including potential cysts –0.19; synovitis 0.23; and popliteal cysts 0.86.

Conclusively, Meniscal extrusion, full thickness cartilage degeneration, and osteophytes are all linked to increased knee discomfort.