Study finds, Risk factors of Postoperative Posterior Segment
A Study was conducted to identify the incidence of, risk factors for, and outcomes of posterior segment complications (PSC) after Boston type 1 keratoprosthesis (KPro) implantation.

The Stein Eye Institute conducted a retrospective, sequential KPro case series. Data have been collected on ocular history, intraoperative details, postoperative treatment and outcomes. The eye was compared with the eyes without the PSC (No Group PSC) with at least one PSC (PSC Group).

--95 PSC occurred in 69/169 eyes, at a mean of 20.1 months after KPro implantation (0.01 complications/eye-month). The median follow-up after KPro implantation was 44.0 months.

--The most common PSC were epiretinal membrane (ERM, 16.6%), cystoid macular edema (CME, 12.4%), vitritis (11.2%) and retinal detachment (RD, 9.5%).

--Previous RD repair, concomitant intraocular lens removal, postoperative aphakia and vitritis were risk factors for RD.

--Postoperative infectious keratitis was a risk factor for ERM, CME and vitritis. PSC Group had a significantly higher rate of eyes failing to maintain visual acuity more than 20/200 (HR = 2.28) and KPro retention failure rate (HR = 1.66).

PSC occurs after implantation in around 40% of the eyes, reducing visual results and maintaining the KPro.