Study finds, Safety Outcomes with Sutured Custom Foldable Si
A Study was conducted to assess the safety and efficacy outcomes of sutured custom silicone artificial iris and intraocular lens implantation combined with penetrating keratoplasty (triple procedure).

Safety outcomes were changes from preoperative to last follow-up in corrected distance visual acuity (CDVA), endothelial cell count, intraocular pressure (IOP), and postoperative complications.

Results:
--Among 82 eyes implanted with an artificial iris, 14 eyes (17.1%) underwent the triple procedure. The median follow-up was 18.1 months.

--The median CDVA improved from 2.0 log of minimum angle of resolution to 0.7 logMAR.

--Average endothelial cell count decreased 57.6%. 6 eyes experienced IOP elevations, 13 eyes developed iritis, and 11 eyes underwent secondary surgery.

--Graft rejection or secondary graft failure occurred in 7 eyes each (50.0%). Cosmesis improved in 12 eyes.

--The Visual Function Questionnaire-25 score improved from 72 to 77. Glare symptoms did not change significantly.

In conclusion, three-fold methods improved CDVA, cosmes, and quality of life; yet they were most commonly related with surgical problems, such as iritis, IOP and secondary injury.

Source: https://journals.lww.com/corneajrnl/Fulltext/2021/10000/Sutured_Custom_Foldable_Silicone_Artificial_Iris.3.aspx
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