Study finds, Septic Arthritis of the Native Knee with increa
Septic arthritis of the native knee often results in irreversible joint damage leading to the need for total knee arthroplasty (TKA). The purpose of the present study was to examine the intermediate-term risk of periprosthetic joint infection (PJI), aseptic revision, and reoperation following primary TKA in patients with a history of septic arthritis of the native knee as compared with primary TKA performed for the treatment of osteoarthritis.

Researchers retrospectively identified 215 primary TKAs in patients with a history of septic arthritis of the native knee. Each case was matched 1:1 based on age, sex, body mass index (BMI), and surgical year to a TKA for osteoarthritis. The mean age and BMI were 63 years and 30 kg/m2, respectively. The mean duration of follow-up was 9 years.

Results:
--Survivorships free of PJI at 10 years were 90% and 99% for the septic arthritis and osteoarthritis groups, respectively.

--Ten-year survivorships free of any aseptic revisions were 83% and 93% (HR = 2.5), and survivorships free of any reoperation were 61% and 84% (HR = 2.9) for the septic arthritis and osteoarthritis groups, respectively.

--In addition, as time from the diagnosis of native knee septic arthritis to TKA increased, the relative risk of subsequent infection decreased.

--Preoperative and 2-year postoperative Knee Society scores were similar between the groups.

When compared to controls undergoing TKA for osteoarthritis, patients getting TKA with a history of native knee septic arthritis had a 6.1-fold greater risk of PJI, with a cumulative incidence of 9% at 10 years. Subgroup analysis of the septic arthritis cohort demonstrated a higher risk of any infection in patients who had TKA within the first 5 to 7 years after being diagnosed with septic arthritis, compared to those who had it for a longer period of time.

Source: https://www.jbjs.org/reader.php?id=209387&rsuite_id=2947183&native=1&source=The_Journal_of_Bone_and_Joint_Surgery/Publish Ahead of Print//10.2106/JBJS.20.01678/abstract&topics=kn#info
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