Study finds, Short-term Functional outcomes after fast-track
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Researchers looked at trends of functional recovery in the first 3 months after TKA and identified non-responders in terms of functional outcome. The early functional outcome following total knee arthroplasty (TKA) has previously been identified, but without a focus on the existence of specific functional recovery trends.

All primary TKA in a fast-track setting with complete patient-reported outcome measures (PROMs) preoperatively, at 6 weeks, and 3 months postoperatively were included. Included PROMs were Oxford Knee Score (OKS), Knee disability and Osteoarthritis Outcome Score Physical Function Short-Form (KOOS-PS), and EuroQol 5 dimensions (EQ-5D) including the self-rated health Visual Analogue Scale (VAS).

Patients who improved on the OKS by less than the minimum clinically significant difference (MCID) at that time were classified as non-responders. Characteristics of responders and non-responders in functional rehabilitation were compared to see if there were any variations.

Results:
623 patients were included.

--At 6 weeks OKS, KOOS-PS, and EQ-5D self-rated health VAS were statistically significantly improved compared with preoperative scores.

--The mean improvement was clinically relevant at 6 weeks for KOOS-PS and at 3 months for OKS.

--Patient characteristics in non-responders were higher BMI and worse scores on EQ-5D items: mobility, self-care, usual activities, and anxiety/depression.

During the first 3 months after primary TKA, most patients showed statistically important and clinically meaningful functional change. BMI and anxiety/depression were suspected modifiable patient characteristics in non-responders on early functional outcome.

Source: https://www.tandfonline.com/doi/full/10.1080/17453674.2021.1925412?af=R
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