Study finds, Temporal Trends in Neurodevelopmental Outcomes
A Study was conducted to examine the changes in major (ie, moderate or severe) neurodevelopmental disability and survival free of major neurodevelopmental disability at 2 years in infants born extremely preterm.

4 prospective longitudinal cohort studies comprising all EP live births at 22 to 27 weeks gestation were included. Among 1208 live births during the periods studied, data were available for analysis of 2-year outcomes in 1152 children.

Results:
--Survival to 2 years was highest in 2016-2017 compared with earlier eras.

--Blindness and deafness were uncommon. Cerebral palsy was less common in 2016-2017 than in earlier eras.

--There were no obvious changes in the rates of developmental quotient less than -2 SDs across eras or in rates of major neurodevelopmental disability.

--Rates of survival free of major neurodevelopmental disability increased steadily over time: 42%, 51%, 53%, and 62%.

These findings suggest that survival free of major disability at age 2 years in children born EP has increased by an absolute 20 % since the early 1990s. Increased survival has not been associated with increased neurodevelopmental disability.

Source: https://jamanetwork.com/journals/jamapediatrics/fullarticle/2782149
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