Study finds incidence, timing and risk factors of Corneal ne
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The purpose of this study was to evaluate the incidence, timing and risk factors of corneal neovascularisation (NV) after deep anterior lamellar keratoplasty (DALK) for corneal ectasia.

DALK was performed on 616 eyes in this study. Topical corticosteroids were stopped in one center after full suture removal 1 year after surgery, while they were stopped in the other 3–4 months after surgery. Slit lamp images were used to determine the incidence and intensity of corneal NV. The Cox proportional hazards model was used to assess potential risk factors for corneal NV.

Results:
--The cumulative incidence of corneal NV was 8.7% at 1 year after surgery and 13.2% at 5 years.

--Mean time interval from surgery to development of corneal NV was 12.8±16.2 months, with 68.9% of cases occurring before complete suture removal.

--Early discontinuation of topical steroids, older age and ocular allergy were associated with an increased risk of developing corneal NV (respectively, HR=2.625, HR=1.019, HR=3.726).

To summarize, the risk of corneal NV is greater in the first year after DALK. Topical steroid discontinuation early, ocular allergy, and advanced age are all important predictors of corneal NV.

Source: https://bjo.bmj.com/content/early/2021/05/12/bjophthalmol-2021-319339?rss=1
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