Study finds, the association of clinical and structural knee
A Study was conducted to investigate if knee osteoarthritis (OA) was associated with lower physical activity in the general middle-aged Dutch population, and if physical activity is associated with patient-reported outcomes in knee OA.

Clinical knee OA was defined in the Netherlands Epidemiology of Obesity population using the ACR criteria, and structural knee OA on MRI. Knee pain and function with the Knee Injury and Osteoarthritis Score (KOOS), health-related quality of life (HRQoL) with the Short Form-36, and physical activity (in Metabolic Equivalent of Task (MET) hours) with the Short Questionnaire to Assess Health-enhancing physical activity was assessed.

--Clinical knee OA was present in 14% of 6,212 participants, (mean age 56 years, mean BMI 27 kg/m2, 55% women, 24% having any comorbidity) and structural knee OA in 12%.

--Clinical knee OA was associated with 9.60 MET hours per week more physical activity, versus no clinical knee OA.

--Structural knee OA was associated with 3.97 MET hours per week more physical activity, versus no structural knee OA.

--In clinical knee OA, physical activity was not associated with knee pain, function or HRQoL.

Exercise levels and patient-reported outcomes in knee osteoarthritis were not linked with each other.