Study reveals post-Covid syndrome severely damages children'
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Multisystem inflammatory syndrome in children (MIS-C), also known as pediatric inflammatory multisystem syndrome, is a new dangerous childhood disease that is temporally associated with coronavirus disease 2019 (COVID-19). A Study was aimed to describe the typical presentation and outcomes of children diagnosed with this hyperinflammatory condition.

A systematic review was conducted to communicate the clinical signs and symptoms, laboratory findings, imaging results, and outcomes of individuals with MIS-C. Search yielded 39 observational studies (n = 662 patients). While 71·0% of children (n = 470) were admitted to the intensive care unit, only 11 deaths (1·7%) were reported. Average length of hospital stay was 7·9 ± 0·6 days.

Fever (100%, n = 662), abdominal pain or diarrhea (73·7%, n = 488), and vomiting (68·3%, n = 452) were the most common clinical presentation. Serum inflammatory, coagulative, and cardiac markers were considerably abnormal. Mechanical ventilation and extracorporeal membrane oxygenation were necessary in 22·2% (n = 147) and 4·4% (n = 29) of patients, respectively. An abnormal echocardiograph was observed in 314 of 581 individuals (54·0%) with depressed ejection fraction (45·1%, n = 262 of 581) comprising the most common aberrancy.

Multisystem inflammatory syndrome is a new pediatric disease associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is dangerous and potentially lethal & damages the heart to such an extent that some children will need lifelong monitoring and interventions. With prompt recognition and medical attention, most children will survive but the long-term outcomes from this condition are presently unknown.

source: https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30271-6/fulltext
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