Varenicline and Cytisine for Alcohol Use Reduction Among People With HIV and Substance Use
This randomized clinical trial compares the effectiveness of varenicline and cytisine with nicotine replacement therapy for reducing alcohol consumption among individuals with HIV who smoke daily and
A clinical trial to test whether three proven smoking cessation treatments could also reduce alcohol intake found no differences between the medications, but the rates of behavior change for alcohol consumption and smoking were high in all treatment groups. Results suggest these medications could play an important role to reduce alcohol use and smoking at the same time. Unexpectedly, nicotine replacement therapy performed as well as the prescription drugs varenicline and cytisine. The study involved 400 people living with HIV. People living with HIV also have a high burden of hepatitis, multi-substance use and mental health issues. Such participants are often excluded from drug trials. If a medication as simple as nicotine replacement could help them, that would be a win.
Source: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2794965#
Source: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2794965#
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